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6. High-Throughput Nanoimprint Fabrication of Shape-Specific, Stimuli-responsive Polymeric Nanocarriers for Drug and Imaging Agent Delivery (Link)
Graduate Student Researchers: Mary C. Moore, Vikramajit Singh, Patrick Jurney
Collaboration:
Sponsors: National Science Foundation
Project Status: Current
5. Shape Specific, Enzyme-Responsive, Nano-Imprinted Particles for Drug Delivery
Graduate Student Researcher: Mary C. Moore
Collaboration:
Sponsors: National Institute of Health
Project Status: Current
4. NER: Nanoimprint Fabrication of Stimuli-responsive Drug Delivery Carriers (Link)
Graduate Student Researchers: Luz Cristal Glanchai, Mary C. Moore
Collaboration:
Sponsors: National Science Foundation
Project Status: Completed
3. Novel Nano and Micro-fabrication Methods for Injectable, Tissue-targeted, Stimuli-responsive Delivery Vehicles: Towards Simultaneous Delivery of Therapeutics and Contrast-agents
Graduate Student Researchers: Luz Cristal Glanchai, Mary C. Moore
Collaboration:
Sponsors: Charles W. Tate & Judy Spence Tate Charitable Foundation through UT Center for Biomedical Engineering
Project Status: Completed
2. Micro-flow Cytometers based on Dielectrophoretic Particle Focusing
Graduate Student Researcher: Choongho Yu
Collaboration: Prof. Peter Gascoyne (UT MD Anderson Cancer Center)
Sponsor: Whitaker Foundation through UT Center for Biomedical Engineering
Project
Status: Completed
Flow cytometry is an important and powerful method for cell analysis that finds wide use in bioindustrial, research and clinical diagnostic applications. Unfortunately, conventional cytometers are very large and expensive devices of considerable complexity that require operation by skilled technicians. The goal of this work is to realize a much simpler type of flow cytometer based on dielectrophoretic particle focusing that will provide proof of concept for microcytometers that are inexpensive, trivial to operate, and suitable for use in both stand-alone analysis and for in-line control applications as part of unattended instruments. The focusing capability of the microcytometer has been demonstrated for micro beads and human leukemia cells. We are currently developing integrated sensing mechanisms based on impedance and optical detection.
Power Point Presentation (open directly in your browser to run the video clip).
1. Integration of Metal Oxide Nanowires for Sensor Systems
Graduate Student Researcher: Choongho Yu
Collaboration: Prof. Z. L. Wang (Georgia Institute of Technology)
Sponsor: UT Research Grant Program
Project Status: Completed
The electrical properties of single-crystal metal oxide nanowires/nanobelts are highly sensitive to gas species due to the high surface-to-volume ratio. This project aims to develop methods for the integration of functionalized metal oxide nanobelts for sensor systems. We have demonstrated nanobelt-MEMS sensors that can detect a nerve agent simulant at a concentration of the low parts per billion (ppb) level and are free from sensor poisoning.
